Clinical Development

Advancing Transformative
Small Molecule Therapeutics

Managed by experienced biotech industry leaders focused on developing novel biological therapies to address unmet clinical needs.

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Therapeutic Focus

Targeting critical pathways in clinical and preclinical stages to protect biological structures and restore organ function.

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Caspase Inhibition

Developing selective inhibitors designed to block caspase activation, key mediators of cell death and chronic inflammation.

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Regenerative Science

Utilizing unique hypoxic cell technologies to produce matrix materials and growth factors that stimulate natural healing.

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Targeted Indications

Pioneering therapies aimed at broad clinical applications across infectious, inflammatory, and orthopedic conditions.

Clinical Pipeline

Our drug development candidate portfolio targeting significant patient needs.

Candidate / Target Indication Discovery Phase 1 Phase 2 Status
EMRICASAN (Pan-Caspase) Infectious Diseases / COVID-19 โœ“ โœ“ โœ“ Phase 1/2 Active
CTS-2017 (Caspase-1) Inflammatory Conditions โœ“ โœ“ โ€” Preclinical / Phase 1
HST-003 (hECM) Joint Cartilage Repair โœ“ โœ“ โœ“ Phase 1/2 Clinical

Driven by Biotech Innovation

Interested in learning more about Histogen's executive leadership, scientific platform, and corporate background?

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